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Human CNOT8 activation kit by CRISPRa

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SKU
GA106224
CNOT8 CRISPRa kit - CRISPR gene activation of human CCR4-NOT transcription complex subunit 8
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA324846 CNOT8 Antibody (C-term)
400 ul
$645.00
RC200225 CNOT8 (Myc-DDK-tagged)-Human CCR4-NOT transcription complex, subunit 8 (CNOT8)
10 ug
$300.00

Other products for "CNOT8"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CNOT8
Locus ID 9337
Components

GA106224G1, CNOT8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106224G2, CNOT8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106224G3, CNOT8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001301073, NM_001301074, NM_001301075, NM_001301077, NM_001301080, NM_001301082, NM_001301083, NM_001301086, NM_004779
UniProt ID Q9UFF9
Synonyms CAF1; Caf1b; CALIF; hCAF1; POP2
Summary Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN400225 CNOT8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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