Human ASIC3 activation kit by CRISPRa

SKU
GA106203
ASIC3 CRISPRa kit - CRISPR gene activation of human acid sensing ion channel subunit 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ASIC3
Locus ID 9311
Components

GA106203G1, ASIC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106203G2, ASIC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106203G3, ASIC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_004769, NM_020321, NM_020322, NR_046401
UniProt ID Q9UHC3
Synonyms ACCN3; DRASIC; SLNAC1; TNaC1
Summary This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. provided by RefSeq, Feb 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN419013 ASIC3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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