Human ITGB1BP1 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | ITGB1BP1 |
| Locus ID | 9270 |
| Components |
GA106183G1, ITGB1BP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA106183G2, ITGB1BP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA106183G3, ITGB1BP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001319066, NM_001319067, NM_001319068, NM_001319069, NM_001319070, NM_004763, NM_022334, NR_134951, NR_134952, NR_134953, NR_134954, NR_134955, NR_134956, NR_134957, NM_001369744, NM_001369746, NM_001369747, NM_001369749, NM_001369745, NM_001369748, NM_001369750 |
| UniProt ID | O14713 |
| Synonyms | ICAP-1A; ICAP-1alpha; ICAP-1B; ICAP1; ICAP1A; ICAP1B |
| Summary | The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. provided by RefSeq, Jan 2016 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN401963 | ITGB1BP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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