Human Rab11 (RAB11B) activation kit by CRISPRa

SKU GA106155

RAB11B CRISPRa kit - CRISPR gene activation of human RAB11B, member RAS oncogene family

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: RAB11B
• Locus ID: 9230
• Components:

  GA106155G1, Rab11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106155G2, Rab11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106155G3, Rab11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004218
• UniProt ID: Q15907
• Synonyms: H-YPT3
• Summary: The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]