Human LGI1 activation kit by CRISPRa

SKU
GA106141
LGI1 CRISPRa kit - CRISPR gene activation of human leucine rich glioma inactivated 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LGI1
Locus ID 9211
Components

GA106141G1, LGI1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106141G2, LGI1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106141G3, LGI1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001308275, NM_001308276, NM_005097, NR_131777
UniProt ID O95970
Synonyms ADLTE; ADPAEF; ADPEAF; EPITEMPIN; EPT; ETL1; IB1099
Summary This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN405340 LGI1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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