Human SLC24A1 activation kit by CRISPRa

SKU GA106125

SLC24A1 CRISPRa kit - CRISPR gene activation of human solute carrier family 24 member 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: SLC24A1
• Locus ID: 9187
• Components:

  GA106125G1, SLC24A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106125G2, SLC24A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106125G3, SLC24A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001254740, NM_001301031, NM_001301032, NM_001301033, NM_004727
• UniProt ID: O60721
• Synonyms: CSNB1D; HsT17412; NCKX; NCKX1; RODX
• Summary: This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. The encoded protein plays an important role in sodium/calcium exchange in retinal rod and cone photoreceptors by mediating the extrusion of one calcium ion and one potassium ion in exchange for four sodium ions. Mutations in this gene may play a role in congenital stationary night blindness. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]