Human DGKI activation kit by CRISPRa

SKU GA106108

DGKI CRISPRa kit - CRISPR gene activation of human diacylglycerol kinase iota

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: DGKI
• Locus ID: 9162
• Components:

  GA106108G1, DGKI gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA106108G2, DGKI gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA106108G3, DGKI gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004717, NM_001321708, NM_001321709, NM_001321710
• UniProt ID: O75912
• Synonyms: DGK-IOTA
• Summary: This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. [provided by RefSeq, Jul 2008]