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Human MTGR1 (CBFA2T2) activation kit by CRISPRa

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SKU
GA106091
CBFA2T2 CRISPRa kit - CRISPR gene activation of human CBFA2/RUNX1 partner transcriptional co-repressor 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA308048 Rabbit polyclonal antibody to CBFA2T2 (core-binding factor, runt domain, alpha subunit 2; translocated to, 2)
100 ul
$665.00
RC202013 CBFA2T2 (Myc-DDK-tagged)-Human core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (CBFA2T2), transcript variant 4
10 ug
$572.00

Other products for "CBFA2T2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CBFA2T2
Locus ID 9139
Components

GA106091G1, MTGR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106091G2, MTGR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106091G3, MTGR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001032999, NM_001039709, NM_005093, NM_175864
UniProt ID O43439
Synonyms EHT; MTGR1; p85; ZMYND3
Summary In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN402013 CBFA2T2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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