Human SGCE activation kit by CRISPRa

SKU
GA105938
SGCE CRISPRa kit - CRISPR gene activation of human sarcoglycan epsilon
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SGCE
Locus ID 8910
Components

GA105938G1, SGCE gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105938G2, SGCE gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105938G3, SGCE gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001099400, NM_001099401, NM_001301139, NM_003919, NM_001346713, NM_001346715, NM_001346717, NM_001346719, NM_001346720, NM_001362809, NM_001362807, NM_001362808
UniProt ID O43556
Synonyms DYT11; ESG
Summary This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene associated with this gene is located on chromosome 2. provided by RefSeq, Oct 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN405363 SGCE - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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