Human PP11 (ENDOU) activation kit by CRISPRa

SKU
GA105937
ENDOU CRISPRa kit - CRISPR gene activation of human endonuclease, poly(U) specific
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ENDOU
Locus ID 8909
Components

GA105937G1, PP11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105937G2, PP11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105937G3, PP11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001172439, NM_001172440, NM_006025
UniProt ID P21128
Synonyms P11; PP11; PRSS26
Summary This gene encodes a protein with endoribonuclease activity that binds polyuridine-enriched single-stranded RNA. This gene was initially characterized based on its high expression in placenta but was mischaracterized as a serine protease. In mouse, this gene promotes tolerance to self-antigens by regulating B cell activation-induced cell death (AICD). The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. provided by RefSeq, Jul 2020
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Other Versions
SKU Description Size Price
KN413481 ENDOU - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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