Human PRPF4B activation kit by CRISPRa

SKU GA105930

PRPF4B CRISPRa kit - CRISPR gene activation of human pre-mRNA processing factor 4B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PRPF4B
• Locus ID: 8899
• Components:

  GA105930G1, PRPF4B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105930G2, PRPF4B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105930G3, PRPF4B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003913, NM_176800, NR_146783, NR_146784, NR_146785
• UniProt ID: Q13523
• Synonyms: dJ1013A10.1; PR4H; PRP4; PRP4H; PRP4K
• Summary: Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008]