Human SQSTM1 activation kit by CRISPRa

SKU
GA105911
SQSTM1 CRISPRa kit - CRISPR gene activation of human sequestosome 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SQSTM1
Locus ID 8878
Components

GA105911G1, SQSTM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105911G2, SQSTM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105911G3, SQSTM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001142298, NM_001142299, NM_003900
UniProt ID Q13501
Synonyms A170; OSIL; p60; p62; p62B; PDB3; ZIP3
Summary This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. provided by RefSeq, Mar 2009
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Other Versions
SKU Description Size Price
KN403214 SQSTM1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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