OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human GALR2 activation kit by CRISPRa

Be the first to review this product
SKU
GA105855
GALR2 CRISPRa kit - CRISPR gene activation of human galanin receptor 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA308347 Rabbit Polyclonal antibody to Galanin Receptor 2 (galanin receptor 2)
100 ul
$665.00
RC222436 GALR2 (Myc-DDK-tagged)-Human galanin receptor 2 (GALR2)
10 ug
$289.00 $457.00

Other products for "GALR2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GALR2
Locus ID 8811
Components

GA105855G1, GALR2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105855G2, GALR2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105855G3, GALR2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_003857
UniProt ID O43603
Synonyms GAL2-R; GALNR2; GALR-2
Summary Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. provided by RefSeq, Jul 2008
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN222436 GALR2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222436BN GALR2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222436LP GALR2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN222436RB GALR2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN422436 GALR2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products