Human SUCLA2 activation kit by CRISPRa

SKU
GA105849
SUCLA2 CRISPRa kit - CRISPR gene activation of human succinate-CoA ligase ADP-forming beta subunit
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SUCLA2
Locus ID 8803
Components

GA105849G1, SUCLA2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105849G2, SUCLA2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105849G3, SUCLA2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003850
UniProt ID Q9P2R7
Synonyms A-BETA; MTDPS5; SCS-betaA
Summary Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN405212 SUCLA2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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