Human SIGLEC5 activation kit by CRISPRa

SKU
GA105829
SIGLEC5 CRISPRa kit - CRISPR gene activation of human sialic acid binding Ig like lectin 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SIGLEC5
Locus ID 8778
Components

GA105829G1, SIGLEC5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105829G2, SIGLEC5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105829G3, SIGLEC5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003830
UniProt ID O15389
Synonyms CD33L2; CD170; OB-BP2; OBBP2; SIGLEC-5
Summary This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. provided by RefSeq, Feb 2012
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Documents
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Other Versions
SKU Description Size Price
KN406610 SIGLEC5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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