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Human ADAM15 activation kit by CRISPRa

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SKU
GA105813
ADAM15 CRISPRa kit - CRISPR gene activation of human ADAM metallopeptidase domain 15
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC200642 ADAM15 (Myc-DDK-tagged)-Human ADAM metallopeptidase domain 15 (ADAM15), transcript variant 2
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Other products for "ADAM15"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ADAM15
Locus ID 8751
Components

GA105813G1, ADAM15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105813G2, ADAM15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105813G3, ADAM15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001261464, NM_001261465, NM_001261466, NM_003815, NM_207191, NM_207194, NM_207195, NM_207196, NM_207197, NR_048577, NR_048578, NR_048579
UniProt ID Q13444
Synonyms MDC15
Summary The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN400642 ADAM15 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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