Human ADAM23 activation kit by CRISPRa

SKU GA105809

ADAM23 CRISPRa kit - CRISPR gene activation of human ADAM metallopeptidase domain 23

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ADAM23
• Locus ID: 8745
• Components:

  GA105809G1, ADAM23 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105809G2, ADAM23 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105809G3, ADAM23 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003812
• UniProt ID: O75077
• Synonyms: MDC-3; MDC3
• Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. It is reported that inactivation of this gene is associated with tumorigenesis in human cancers. [provided by RefSeq, May 2013]