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Human TWEAK (TNFSF12) activation kit by CRISPRa

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SKU
GA105806
TNFSF12 CRISPRa kit - CRISPR gene activation of human TNF superfamily member 12
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ug
$640.00
RC221007 TNFSF12 (Myc-DDK-tagged)-Human tumor necrosis factor (ligand) superfamily, member 12 (TNFSF12), transcript variant 1
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Other products for "TNFSF12"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TNFSF12
Locus ID 8742
Components

GA105806G1, TWEAK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105806G2, TWEAK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105806G3, TWEAK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003809, NM_153012, NR_037146
UniProt ID O43508
Synonyms APO3L; DR3LG; TWEAK
Summary The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. provided by RefSeq, Oct 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN421007 TNFSF12 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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