Human HRK activation kit by CRISPRa

SKU GA105803

HRK CRISPRa kit - CRISPR gene activation of human harakiri, BCL2 interacting protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: HRK
• Locus ID: 8739
• Components:

  GA105803G1, HRK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105803G2, HRK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105803G3, HRK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003806, NR_073189
• UniProt ID: O00198
• Synonyms: DP5; HARAKIRI
• Summary: This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]