Human EIF3S4 (EIF3G) activation kit by CRISPRa

SKU GA105746

EIF3G CRISPRa kit - CRISPR gene activation of human eukaryotic translation initiation factor 3 subunit G

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: EIF3G
• Locus ID: 8666
• Components:

  GA105746G1, EIF3S4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105746G2, EIF3S4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105746G3, EIF3S4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003755
• UniProt ID: O75821
• Synonyms: eIF3-delta; EIF3-P42; eIF3-p44; EIF3S4
• Summary: This gene encodes a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex, which is required for initiation of protein translation. An N-terminal caspase cleavage product of the encoded protein may stimulate degradation of DNA. A mutation in this gene is associated with narcolepsy. [provided by RefSeq, Jul 2016]