Human IRS2 activation kit by CRISPRa

SKU
GA105740
IRS2 CRISPRa kit - CRISPR gene activation of human insulin receptor substrate 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IRS2
Locus ID 8660
Components

GA105740G1, IRS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105740G2, IRS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105740G3, IRS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003749
UniProt ID Q9Y4H2
Synonyms IRS-2
Summary This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN412413 IRS2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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