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Human SOCS1 activation kit by CRISPRa

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SKU
GA105734
SOCS1 CRISPRa kit - CRISPR gene activation of human suppressor of cytokine signaling 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC220847 SOCS1 (Myc-DDK-tagged)-Human suppressor of cytokine signaling 1 (SOCS1)
10 ug
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SOCS1
Locus ID 8651
Components

GA105734G1, SOCS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105734G2, SOCS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105734G3, SOCS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003745
UniProt ID O15524
Synonyms CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP3
Summary This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN420847 SOCS1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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