Human OASL activation kit by CRISPRa

SKU GA105722

OASL CRISPRa kit - CRISPR gene activation of human 2'-5'-oligoadenylate synthetase like

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: OASL
• Locus ID: 8638
• Components:

  GA105722G1, OASL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105722G2, OASL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105722G3, OASL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001261825, NM_003733, NM_198213
• UniProt ID: Q15646
• Synonyms: OASLd; p59 OASL; p59-OASL; p59OASL; TRIP-14; TRIP14
• Summary: Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.[UniProtKB/Swiss-Prot Function]