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Human DENN (MADD) activation kit by CRISPRa

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SKU
GA105678
MADD CRISPRa kit - CRISPR gene activation of human MAP kinase activating death domain
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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Other products for "MADD"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MADD
Locus ID 8567
Components

GA105678G1, DENN gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105678G2, DENN gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105678G3, DENN gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001135943, NM_001135944, NM_003682, NM_130470, NM_130471, NM_130472, NM_130473, NM_130474, NM_130475, NM_130476
UniProt ID Q8WXG6
Synonyms DENN; IG20; RAB3GEP
Summary Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN406061 MADD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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