Human PDXK activation kit by CRISPRa

SKU GA105677

PDXK CRISPRa kit - CRISPR gene activation of human pyridoxal kinase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PDXK
• Locus ID: 8566
• Components:

  GA105677G1, PDXK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105677G2, PDXK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105677G3, PDXK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003681, NM_001331030
• UniProt ID: O00764
• Synonyms: C21orf97; C21orf124; HEL-S-1a; PKH; PNK; PRED79
• Summary: The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]