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Human CILP activation kit by CRISPRa

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SKU
GA105606
CILP CRISPRa kit - CRISPR gene activation of human cartilage intermediate layer protein
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "CILP"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CILP
Locus ID 8483
Components

GA105606G1, CILP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105606G2, CILP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105606G3, CILP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003613
UniProt ID O75339
Synonyms CILP-1; HsT18872
Summary Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. provided by RefSeq, Sep 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN407801 CILP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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