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Human CDC45L (CDC45) activation kit by CRISPRa

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SKU
GA105484
CDC45 CRISPRa kit - CRISPR gene activation of human cell division cycle 45
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC202442 CDC45 (Myc-DDK-tagged)-Human cell division cycle 45 homolog (S. cerevisiae) (CDC45), transcript variant 2
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Other products for "CDC45"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CDC45
Locus ID 8318
Components

GA105484G1, CDC45L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105484G2, CDC45L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105484G3, CDC45L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001178010, NM_001178011, NM_003504, NM_001369291, NR_161281
UniProt ID O75419
Synonyms CDC45L; CDC45L2; PORC-PI-1
Summary The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. provided by RefSeq, Jul 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN402442 CDC45 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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