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Human ELL activation kit by CRISPRa

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SKU
GA105430
ELL CRISPRa kit - CRISPR gene activation of human elongation factor for RNA polymerase II
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA810799 ELL mouse monoclonal antibody,clone OTI2H7 100 ul
$447.00
RC208258 ELL (Myc-DDK-tagged)-Human elongation factor RNA polymerase II (ELL)
10 ug
$867.00

Other products for "ELL"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ELL
Locus ID 8178
Components

GA105430G1, ELL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105430G2, ELL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105430G3, ELL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006532
UniProt ID P55199
Synonyms C19orf17; ELL1; MEN; PPP1R68
Summary Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN408258 ELL - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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