Human CSRP3 activation kit by CRISPRa

SKU GA105395

CSRP3 CRISPRa kit - CRISPR gene activation of human cysteine and glycine rich protein 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CSRP3
• Locus ID: 8048
• Components:

  GA105395G1, CSRP3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105395G2, CSRP3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105395G3, CSRP3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001127656, NM_003476, NM_001369404
• UniProt ID: P50461
• Synonyms: CLP; CMD1M; CMH12; CRP3; LMO4; MLP
• Summary: This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]