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Human HSD17B8 activation kit by CRISPRa

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SKU
GA105360
HSD17B8 CRISPRa kit - CRISPR gene activation of human hydroxysteroid 17-beta dehydrogenase 8
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA800478 HSD17B8 mouse monoclonal antibody, clone OTI2E12 (formerly 2E12) 100 ul
$447.00
RC203806 HSD17B8 (Myc-DDK-tagged)-Human hydroxysteroid (17-beta) dehydrogenase 8 (HSD17B8)
10 ug
$300.00

Other products for "HSD17B8"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HSD17B8
Locus ID 7923
Components

GA105360G1, HSD17B8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105360G2, HSD17B8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105360G3, HSD17B8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_014234
UniProt ID Q92506
Synonyms D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; KE6; RING2; SDR30C1
Summary In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN403806 HSD17B8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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