Human CXCR4 activation kit by CRISPRa

SKU
GA105337
CXCR4 CRISPRa kit - CRISPR gene activation of human C-X-C motif chemokine receptor 4
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CXCR4
Locus ID 7852
Components

GA105337G1, CXCR4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105337G2, CXCR4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105337G3, CXCR4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001008540, NM_003467, NM_001348056, NM_001348059, NM_001348060
UniProt ID P61073
Synonyms CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM
Summary This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq, Jul 2008
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Other Versions
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KN202069 CXCR4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN202069BN CXCR4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN202069LP CXCR4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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KN202069RB CXCR4 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN402069 CXCR4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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