Human NPHS2 activation kit by CRISPRa

SKU GA105327

NPHS2 CRISPRa kit - CRISPR gene activation of human NPHS2 stomatin family member, podocin

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NPHS2
• Locus ID: 7827
• Components:

  GA105327G1, NPHS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105327G2, NPHS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105327G3, NPHS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001297575, NM_014625
• UniProt ID: Q9NP85
• Synonyms: PDCN; SRN1
• Summary: This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]