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Human ZFAND5 activation kit by CRISPRa

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SKU
GA105296
ZFAND5 CRISPRa kit - CRISPR gene activation of human zinc finger AN1-type containing 5
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC209943 ZFAND5 (Myc-DDK-tagged)-Human zinc finger, AN1-type domain 5 (ZFAND5), transcript variant c
10 ug
$300.00

Other products for "ZFAND5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ZFAND5
Locus ID 7763
Components

GA105296G1, ZFAND5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105296G2, ZFAND5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105296G3, ZFAND5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001102420, NM_001102421, NM_001278243, NM_001278244, NM_001278245, NM_006007
UniProt ID O76080
Synonyms ZA20D2; ZFAND5A; ZNF216
Summary Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN409943 ZFAND5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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