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Human Mel18 (PCGF2) activation kit by CRISPRa

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SKU
GA105262
PCGF2 CRISPRa kit - CRISPR gene activation of human polycomb group ring finger 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA302537 Goat Polyclonal Antibody against MEL18 / PCGF2
100 ug
$565.00
RC202490 PCGF2 (Myc-DDK-tagged)-Human polycomb group ring finger 2 (PCGF2)
10 ug
$457.00

Other products for "PCGF2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PCGF2
Locus ID 7703
Components

GA105262G1, Mel18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105262G2, Mel18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105262G3, Mel18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_007144, NM_001369614, NM_001369615
UniProt ID P35227
Synonyms MEL-18; RNF110; ZNF144
Summary The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN402490 PCGF2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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