Human CNBP activation kit by CRISPRa

SKU GA105202

CNBP CRISPRa kit - CRISPR gene activation of human CCHC-type zinc finger nucleic acid binding protein

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CNBP
• Locus ID: 7555
• Components:

  GA105202G1, CNBP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105202G2, CNBP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105202G3, CNBP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001127192, NM_001127193, NM_001127194, NM_001127195, NM_001127196, NM_003418
• UniProt ID: P62633
• Synonyms: CNBP1; DM2; PROMM; RNF163; ZCCHC22; ZNF9
• Summary: This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]