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Human VRK1 activation kit by CRISPRa

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SKU
GA105130
VRK1 CRISPRa kit - CRISPR gene activation of human VRK serine/threonine kinase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA805595 VRK1 mouse monoclonal antibody, clone OTI2C9 (formerly 2C9) 100 ul
$447.00
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$457.00

Other products for "VRK1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol VRK1
Locus ID 7443
Components

GA105130G1, VRK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105130G2, VRK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105130G3, VRK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003384
UniProt ID Q99986
Synonyms PCH1; PCH1A
Summary This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN410764 VRK1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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