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Human VAV1 activation kit by CRISPRa

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SKU
GA105105
VAV1 CRISPRa kit - CRISPR gene activation of human vav guanine nucleotide exchange factor 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA308739 Rabbit polyclonal antibody to VAV1 (vav 1 guanine nucleotide exchange factor)
100 ul
$665.00
RC224806 VAV1 (Myc-DDK-tagged)-Human vav 1 guanine nucleotide exchange factor (VAV1)
10 ug
$1,160.00

Other products for "VAV1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol VAV1
Locus ID 7409
Components

GA105105G1, VAV1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105105G2, VAV1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105105G3, VAV1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001258206, NM_001258207, NM_005428
UniProt ID P15498
Synonyms VAV
Summary This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Apr 2012
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Other Versions
SKU Description Size Price
KN424806 VAV1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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