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Human UCP2 activation kit by CRISPRa

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SKU
GA105063
UCP2 CRISPRa kit - CRISPR gene activation of human uncoupling protein 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA302628 Goat Polyclonal Antibody against Uncoupling protein 2 / UCP2
100 ug
$565.00
RC203997 UCP2 (Myc-DDK-tagged)-Human uncoupling protein 2 (mitochondrial, proton carrier) (UCP2), nuclear gene encoding mitochondrial protein
10 ug
$450.00

Other products for "UCP2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol UCP2
Locus ID 7351
Components

GA105063G1, UCP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105063G2, UCP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105063G3, UCP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003355
UniProt ID P55851
Synonyms BMIQ4; SLC25A8; UCPH
Summary Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN403997 UCP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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