Human UBE2L3 activation kit by CRISPRa

SKU
GA105050
UBE2L3 CRISPRa kit - CRISPR gene activation of human ubiquitin conjugating enzyme E2 L3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol UBE2L3
Locus ID 7332
Components

GA105050G1, UBE2L3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105050G2, UBE2L3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105050G3, UBE2L3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001256355, NM_001256356, NM_003347, NM_198157, NR_028436, NR_028437, NR_046082
UniProt ID P68036
Synonyms E2-F1; L-UBC; UBCH7; UbcM4
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Sep 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN408780 UBE2L3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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