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Human UBE2D2 activation kit by CRISPRa

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SKU
GA105042
UBE2D2 CRISPRa kit - CRISPR gene activation of human ubiquitin conjugating enzyme E2 D2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA806600 UBE2D2 mouse monoclonal antibody, clone OTI2C2 (formerly 2C2) 100 ul
$447.00
RC218795 UBE2D2 (Myc-DDK-tagged)-Human ubiquitin-conjugating enzyme E2D 2 (UBE2D2), transcript variant 1
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Other products for "UBE2D2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol UBE2D2
Locus ID 7322
Components

GA105042G1, UBE2D2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105042G2, UBE2D2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105042G3, UBE2D2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003339, NM_181838
UniProt ID P62837
Synonyms E2(17)KB2; PUBC1; UBC4; UBC4/5; UBCH4; UBCH5B
Summary Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. provided by RefSeq, May 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN407283 UBE2D2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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