UBE2D2 Mouse Monoclonal Antibody [Clone ID: OTI2C2]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI2C2 |
|---|---|
| Application | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human UBE2D2 (NP_003330) produced in E.coli. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 16.6 kDa |
| Gene Name | ubiquitin conjugating enzyme E2 D2 |
| Database Link | |
| Background | Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. provided by RefSeq, May 2013 |
| Synonyms | E2(17)KB2; PUBC1; UBC4; UBC4/5; UBCH4; UBCH5B |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Ubiquitin mediated proteolysis |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
Other "OTI2C2" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF806600 | Carrier-free (BSA/glycerol-free) UBE2D2 mouse monoclonal antibody, clone OTI2C2 (formerly 2C2) | 100 ug |
$620.00
|
|
| TA806600AM | UBE2D2 mouse monoclonal antibody, clone OTI2C2 (formerly 2C2), Biotinylated | 100 ul |
$509.00
|
|
| TA806600BM | UBE2D2 mouse monoclonal antibody, clone OTI2C2 (formerly 2C2), HRP conjugated | 100 ul |
$509.00
|
|
| TA806600S | UBE2D2 mouse monoclonal antibody, clone OTI2C2 (formerly 2C2) | 30 ul |
$200.00
|
|
Citations
Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB
King, Cho, Hsu et al
Cell Chem Biol (2023) 30 (4), 394-402.e9 DOI: 10.1016/j.chembiol.2023.02.008
King, Cho, Hsu et al
Cell Chem Biol (2023) 30 (4), 394-402.e9 DOI: 10.1016/j.chembiol.2023.02.008
Cited by 103
Showing 1-1 of 1 papers.
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