Human Rad6 (UBE2A) activation kit by CRISPRa

SKU
GA105039
UBE2A CRISPRa kit - CRISPR gene activation of human ubiquitin conjugating enzyme E2 A
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol UBE2A
Locus ID 7319
Components

GA105039G1, Rad6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105039G2, Rad6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105039G3, Rad6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001282161, NM_003336, NM_181762, NM_181777
UniProt ID P49459
Synonyms HHR6A; MRXS30; MRXSN; RAD6A; UBC2
Summary The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with cognitive disability. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2013
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Documents
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Other Versions
SKU Description Size Price
KN404194 UBE2A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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