Human TUB activation kit by CRISPRa

SKU GA105009

TUB CRISPRa kit - CRISPR gene activation of human TUB bipartite transcription factor

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TUB
• Locus ID: 7275
• Components:

  GA105009G1, TUB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105009G2, TUB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105009G3, TUB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003320, NM_177972
• UniProt ID: P50607
• Synonyms: rd5; RDOB
• Summary: This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]