TUB Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | WB, IHC |
Reactivity | Human |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for Anti-TUB Antibody: synthetic peptide directed towards the N terminal of human TUB. Synthetic peptide located within the following region: DSLASVQLGATRPTAPASAKRTKAAATAGGQGGAARKEKKGKHKGTSGPA |
Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 62 kDa |
Gene Name | tubby bipartite transcription factor |
Database Link | |
Background | TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. |
Synonyms | rd5; RDOB |
Note | Immunogen sequence homology: Human: 100%; Dog: 92%; Rat: 92%; Mouse: 92%; Rabbit: 92%; Pig: 85%; Horse: 85%; Guinea pig: 85% |
Reference Data |
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