TUB Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB, IHC |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The immunogen for Anti-TUB Antibody: synthetic peptide directed towards the N terminal of human TUB. Synthetic peptide located within the following region: DSLASVQLGATRPTAPASAKRTKAAATAGGQGGAARKEKKGKHKGTSGPA |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 62 kDa |
| Gene Name | tubby bipartite transcription factor |
| Database Link | |
| Background | TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. |
| Synonyms | rd5; RDOB |
| Note | Immunogen sequence homology: Human: 100%; Dog: 92%; Rat: 92%; Mouse: 92%; Rabbit: 92%; Pig: 85%; Horse: 85%; Guinea pig: 85% |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
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Citations
Prostate apoptosis response-4 is involved in the apoptosis response to docetaxel in MCF-7 breast cancer cells
Pereira, de Bessa-Garcia, Burikhanov et al
Int. J. Oncol. (2013) 43 (2), 531-8 DOI: 10.3892/ijo.2013.1983
Pereira, de Bessa-Garcia, Burikhanov et al
Int. J. Oncol. (2013) 43 (2), 531-8 DOI: 10.3892/ijo.2013.1983
Cited by 36
AI Summary: OriGene products, specifically the pcCMV6-XL6-Par-4 (full-length Par-4 cDNA expression vector) and the pcCMV6-XL6-Neo (empty vector), were used to manipulate Par-4 expression in MCF-7 breast cancer cells, enabling the study of Par-4's role in cell proliferation, apoptosis, and response to docetaxel.
Snippet: with 100 U/ml penicillin, 100 µg/ml streptomycin, 0.25 µg/ml fungizon and 10% fetal bovine serum (FBS) (Invitrogen Life Technologies, Carlsbad ... pcCMV6-XL6-Par-4 expressing a full length Par-4 cDNA, or empty vector (pcCMV6-XL6-Neo) acquired from OriGene (Rockville, MD
Showing 1-1 of 1 papers.
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