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Human Translin (TSN) activation kit by CRISPRa

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SKU
GA104985
TSN CRISPRa kit - CRISPR gene activation of human translin
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA809099 TSN mouse monoclonal antibody,clone OTI1B5 100 ul
$447.00
RC201804 TSN (Myc-DDK-tagged)-Human translin (TSN)
10 ug
$300.00

Other products for "TSN"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TSN
Locus ID 7247
Components

GA104985G1, Translin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104985G2, Translin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104985G3, Translin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001261401, NM_004622, NR_048556, NR_048557, NR_048558, NR_048559
UniProt ID Q15631
Synonyms BCLF-1; C3PO; RCHF1; REHF-1; TBRBP; TRSLN
Summary This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. provided by RefSeq, May 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN401804 TSN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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