Human TRPS1 activation kit by CRISPRa

SKU GA104984

TRPS1 CRISPRa kit - CRISPR gene activation of human transcriptional repressor GATA binding 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TRPS1
• Locus ID: 7227
• Components:

  GA104984G1, TRPS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104984G2, TRPS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104984G3, TRPS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001282902, NM_001282903, NM_014112, NM_001330599
• UniProt ID: Q9UHF7
• Synonyms: GC79; LGCR
• Summary: This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq, Jul 2008]