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Human TPM1 activation kit by CRISPRa

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SKU
GA104952
TPM1 CRISPRa kit - CRISPR gene activation of human tropomyosin 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA323683 Anti-TPM1 Rabbit Polyclonal Antibody
100 ul
$305.00
RC201262 TPM1 (Myc-DDK-tagged)-Human tropomyosin 1 (alpha) (TPM1), transcript variant 5
10 ug
$300.00

Other products for "TPM1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TPM1
Locus ID 7168
Components

GA104952G1, TPM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104952G2, TPM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104952G3, TPM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000366, NM_001018004, NM_001018005, NM_001018006, NM_001018007, NM_001018008, NM_001018020, NM_001301244, NM_001301289, NM_001330344, NM_001330346, NM_001330351, NM_001365777, NM_001365778, NM_001365779, NM_001365782, NM_001365776, NM_001365780, NM_001365781
UniProt ID P09493
Synonyms C15orf13; CMD1Y; CMH3; HEL-S-265; HTM-alpha; LVNC9; TMSA
Summary This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN401262 TPM1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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