Human TSPAN6 activation kit by CRISPRa

SKU
GA104906
TSPAN6 CRISPRa kit - CRISPR gene activation of human tetraspanin 6
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TSPAN6
Locus ID 7105
Components

GA104906G1, TSPAN6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104906G2, TSPAN6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104906G3, TSPAN6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001278740, NM_001278741, NM_001278742, NM_001278743, NM_003270, N64145
UniProt ID O43657
Synonyms T245; TM4SF6; TSPAN-6
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. provided by RefSeq, Jul 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN402014 TSPAN6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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