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Human TLR1 activation kit by CRISPRa

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SKU
GA104897
TLR1 CRISPRa kit - CRISPR gene activation of human toll like receptor 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC215218 TLR1 (Myc-DDK-tagged)-Human toll-like receptor 1 (TLR1)
10 ug
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TLR1
Locus ID 7096
Components

GA104897G1, TLR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104897G2, TLR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104897G3, TLR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_003263
UniProt ID Q15399
Synonyms CD281; rsc786; TIL; TIL. LPRS5
Summary The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
KN415218 TLR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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