Human Thymidine Kinase 2 (TK2) activation kit by CRISPRa

SKU
GA104886
TK2 CRISPRa kit - CRISPR gene activation of human thymidine kinase 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TK2
Locus ID 7084
Components

GA104886G1, Thymidine Kinase 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104886G2, Thymidine Kinase 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104886G3, Thymidine Kinase 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001172643, NM_001172644, NM_001172645, NM_001271934, NM_001271935, NM_001272050, NM_004614, NR_073520, NR_073521
UniProt ID O00142
Synonyms MTDPS2; MTTK; SCA31
Summary This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria. provided by RefSeq, Dec 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN423312 TK2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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